Squamous cell carcinoma is a well-differentiated, low-grade malignant carcinoma.  first described by Ackermann in 1948, which defined clinical and histological criteria [2]. The preferred sites for this type of carcinoma are the skin, esophagus, oral cavity, larynx, plantar surface, and genitals [2]. intertrigo localization is exceptional. Tumor occurring most frequently at the level of the last two interdigital spaces in benign chronic lesions that do not respond to specific treatment and most predominantly in lesions of mycotic intertrigo.

An etiology of verrucous carcinoma remains less clear, some publications have reported the factors that favour the development of Squamous cell carcinoma at the intertrigo, with maceration being considered the main an etiological factor [3]. The other causes, especially chronic inflammation such as psoriasis, traumatization, Human papilloma virus (HPV) has been associated with this tumor and specifically HPV types 11 and 16 have been described in plantar lesions [4].  remain unexplained.

But in most cases reported in the literature, interdigital squamous cell carcinoma has been considered as an intertrigo mycosis [2,3],

The clinical appearance is that of vegetative, exophytic tumors with a verrucous and ulcerated surface with keratinous debris and an infiltrated base extending beyond the visible limits of the tumor. The tumor then expands in surface and height by overflowing the dorsal side of the feet.

The dermoscopy findings of verrucous carcinoma are the presence of a white background (amorphous keratinous masses, yellowish white to light brown), a verrucous appearance, a polymorphous vascular pattern with more than one type of vessel dominating (consisting of linear, irregular, hairpin, glomerular and, rarely, dotted types), and ulceration.

The most common differential diagnoses are, verrucous leishmaniasis, Bowen's disease, verrucous tuberculosis, verruca vulgaris, deep mycoses, atypical mycobacteriosis, and common warts [5].

Histological features of verrucous carcinoma include a papillomatous surface and broad, blunt tongues of epithelial tissue extending into the dermis, few cytological atypia, mitoses are usually limited to the basal layer and are few, presence of neutrophils [6], which makes difficult the distinction with psedo-epitheliomatous hyperplasia and common wart [7]. The prognosis of Verrucous Carcinoma (VC) is often favorable but local invasiveness and

The progress is mainly local with a rare risk of bone lysis [6]. Metastatic risk is low Surgical excision is the treatment of the choice. Clinical follow-up of these patients is very essential, as recurrences are common even after surgery.